What may be elevated in atopic dermatitis?

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Multiple Choice

What may be elevated in atopic dermatitis?

Explanation:
Atopic dermatitis is driven by an allergic-type immune response that often shows a rise in IgE and in eosinophils. Th2 cytokines like IL-4 and IL-13 push B cells to produce more IgE, which sensitizes the skin to allergens. IL-5 then promotes eosinophil production and recruitment to inflamed skin. Because of this, the combination of elevated IgE and eosinophilia is typical in this condition. IgA or IgG aren’t defining features of atopy, and eosinophils aren’t typically decreased in this inflammatory setting.

Atopic dermatitis is driven by an allergic-type immune response that often shows a rise in IgE and in eosinophils. Th2 cytokines like IL-4 and IL-13 push B cells to produce more IgE, which sensitizes the skin to allergens. IL-5 then promotes eosinophil production and recruitment to inflamed skin. Because of this, the combination of elevated IgE and eosinophilia is typical in this condition. IgA or IgG aren’t defining features of atopy, and eosinophils aren’t typically decreased in this inflammatory setting.

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